Calcium L-Threonate
Introduction
Calcium L-Threonate is a highly bioavailable form of calcium, with the chemical formula C₈H₁₄CaO₁₀ and CAS No. 70753-61-6. It is a calcium salt of L-threonic acid, a metabolite of Vitamin C (ascorbic acid) in the human body. This form of calcium is recognized for its superior absorption and retention compared to conventional calcium supplements, making it an ideal choice for bone health formulations.
Unlike many inorganic calcium sources (e.g., calcium carbonate, calcium phosphate), Calcium L-Threonate offers gentle gastrointestinal tolerance and does not require gastric acid for dissolution. It is readily soluble in water, has a neutral taste, and is suitable for both solid and liquid formulations.
Commercial production typically involves fermentation or synthesis of L-threonic acid from Vitamin C, followed by neutralization with calcium salts under controlled conditions, and subsequent purification and crystallization. The result is a white to off-white crystalline powder with excellent stability under normal storage conditions.
Calcium L-Threonate has gained popularity in nutraceutical markets globally for bone density support, joint health, and as part of comprehensive calcium–collagen–vitamin D formulas. Its clean-label, non-GMO, and often vegan-suitable profile makes it appealing for premium dietary supplement brands.
Typical Specifications
|
Item |
Specification |
|
Assay (Calcium L-Threonate, HPLC) |
≥98.0% |
|
Calcium Content |
12.5–13.5% |
|
Appearance |
White to off-white crystalline powder |
|
Identification |
HPLC/IR spectrum consistent with reference |
|
Loss on Drying |
≤1.0% |
|
pH (1% solution) |
5.0–7.0 |
|
Heavy Metals |
≤10 ppm |
|
Microbiology |
TPC ≤1,000 cfu/g; Yeast & Mold ≤100 cfu/g; E. coli/Salmonella: Negative |
|
Solubility |
Freely soluble in water |
|
Packaging |
25 kg fiber drum or customized packaging |
|
Storage |
Store in a cool, dry place; protect from light and moisture |
Benefits
✓ High bioavailability — enhances calcium absorption and retention in bones
✓ Supports bone density and overall skeletal health
✓ Gentle on digestion — suitable for individuals sensitive to other calcium forms
Application
Nutraceuticals: Capsules, tablets, chewables, and powder blends for bone and joint health
Functional Beverages:Calcium-enriched drinks and liquid supplements
Fortified Foods: Added to dairy alternatives, nutrition bars, and meal replacements
Product Processing













