Hyaluronic Acid (HA)

Product Name Hyaluronic Acid
CAS No 9004-61-9
MF (C14H21NO11)n
Specification 99%
Test Method HPLC
Shelf Time 2 years
Package 25kg/Drum
Certificates HACCP, ISO22000, Kosher, Halal, FDA, SGS

product details

Description

Hyaluronic Acid (HA) is a linear glycosaminoglycan composed of repeating disaccharide units (D-glucuronic acid and N-acetyl-D-glucosamine). Naturally present in connective tissues (skin, joints, eyes), it exhibits unparalleled water-binding capacity due to its hygroscopic structure.

Molecular Formula: (C₁₄H₂₁NO₁₁)ₙ

Polymer Length: 2,500–25,000 disaccharide repeats (varies by source)

Tissue Distribution:
Skin (50% of total body HA) – 0.5 mg/g in dermis
Synovial fluid (3–4 mg/mL)
Vitreous humor (eye) – 0.1–0.4 mg/mL

Physicochemical Properties

Property	Value	Significance
Water-Binding Capacity	1,000× its weight	Highest among natural polymers
Viscosity (1% solution)	2,000–10,000 cP	Ideal for lubricating applications
pH Stability	5.0–9.0	Compatible with cosmetic formulations
Thermal Degradation	>100°C	Stable in most processing conditions

Production Methods Comparison

Method	Yield	Purity	Key Advantage
Microbial Fermentation	6–10 g/L	>95%	Scalable, animal-free
Tremella fuciformis	5–8% of biomass	80–90%	Vegan, no endotoxin risk
Rooster Comb Extraction	0.5–1%	70–85%	Traditional, higher MW HA

Molecular Weight-Specific Effects

MW Range	Skin Penetration	Primary Benefit
>1,000 kDa	Stratum corneum	Film-forming, moisture barrier
50–1,000 kDa	Epidermis	Hydration, elasticity boost
<50 kDa	Dermis	Fibroblast activation, collagen synthesis

Benefits

✔ Deep Hydration – Locks moisture into skin layers

✔ Joint Lubrication – Enhances synovial fluid viscosity

✔ Wound Healing – Accelerates tissue regeneration

✔ Anti-Aging – Plumps fine lines & improves elasticity

✔ Biodegradable – Naturally metabolized by the body

Applications

Cosmeceuticals:
Serums (e.g., 1–2% HA in The Ordinary Hyaluronic Acid Serum)
Injectable fillers (cross-linked HA for volumizing)

Nutraceuticals:
Oral supplements (100–200 mg/day for joint/skin health)
Functional beverages (HA-infused collagen drinks)

Medical:
Osteoarthritis treatments (viscosupplementation)
Ophthalmology (eye surgery lubricants)

Product Processing

Standard and Certificates

All of our products are made in a GMP-compliant facility where every step of production is carefully managed. Over the years, our factory has passed several well-recognized audits, including HACCP, ISO22000 and ISO9001. The products also meet Kosher and Halal requirements, and we hold FDA registration as well. These certifications reflect the standards we follow rather than just labels we collect—they’re part of how we ensure consistency and safety in every batch.

Free Sample Available

If you’d like to get a feel for the product before placing an order, we can send you a free sample. In most cases, we provide around 10–20 grams so you can evaluate the quality yourself. For items with higher raw material costs, we will confirm the exact amount we can offer so everything is clear before shipping.

Standard Packaging and Private Label

For regular shipments, we usually pack goods in 1–5 kg aluminum foil bags, 10–20 kg cartons, or 10–30 kg fiber drums, depending on the item and order size.

If you’re planning to sell under your own brand, we also handle private labeling. We can help design and produce packaging with your logo or artwork so the products arrive ready for retail. Many customers find this saves them a lot of time compared with printing and repacking on their end.

Shipping Method

Orders under one metric ton are generally shipped through major express couriers such as DHL, FedEx, UPS or EMS. For larger quantities, we can arrange transport by sea or railway. The best method depends on your location and how quickly you need the goods, so we’ll help you choose the most practical option.

After Sale Services

Most of our products remain stable for up to two years, and we guarantee their quality within that period. If anything arrives below your expectations, our return process is straightforward. You can send back the portion in question, and we will refund the corresponding amount—no complicated procedures or hidden conditions.